Figure 3.

XBJ decreased the inflammatory response in MRSA-infected mice. C57BL/6J female mice were randomly divided into seven groups (N=6/group). All groups of mice were intraperitoneally injected with MRSA (4 × 10⁸ CFU/mouse) and XBJ (5 ml/kg), DXM (7 mg/kg), VAN (110 mg/kg), and their combination in corresponding groups. After 12 hours, blood samples were collected from eyeball, standing still at 4℃ for 3 hours, and then centrifuged for 25 minutes (3500 rpm, 4°C) to obtain sera. The concentrations of IL-6 (A), TNF-α (B), MCP-1 (C), MIP-2 (D)) and IL-10 (E) were detected by ELISA. Data were shown as mean ± SD of six mice per group. *^,**^,***Significantly different at p < 0.05, p < 0.01, and p < 0.001, respectively.