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. 2020 Feb 27;6(2):e03473. doi: 10.1016/j.heliyon.2020.e03473

Table 2.

Median viral load stratified by patient demographic and clinical characteristics assessed by the Kruskal-Wallis rank test.

Characteristic HPV 16 (Total = 80)
HPV 18 (Total = 46)
Copies/μL (n) Copies/μL (n)
Age, years

 ≤30 540.3 (5) 2 (4)
 31–45 202.8 (27) 8 (21)
 46–60 292.1 (27) 326 (18)
 >60 728.2 (21) 61.84 (3)
 Kruskal-Wallis (P value) (0.092) (0.47)

Marital status

 Married 350.11 (57) 13 (41)
 Divorced 1824.61 (3) 15.37 (2)
 Widowed 524.708 (15) 1375.2 (1)
 Single 281.68 (5) 16,191,521 (2)
 Kruskal-Wallis (P value) (0.24) (0.186)

Cytology grade

 Normal 0.73 (14) 2 (31)
 ASCUS 0.008 (1) 1.90 (1)
 LGSIL 284.39 (1) 1.19 (1)
 HGSIL 218.1 (15) 33,850,583 (2)
 Cervical cancer 783 (49) 582 (11)
 Kruskal-Wallis (P value) (0.001) ∗∗ (0.011) ∗∗

Cytology outcome

 Normal 0.72 2
 Abnormal 525.9 442.82
 MW (P value) (0.001) ∗∗ (0.002) ∗∗

Infection Type

 Single 525.9 15.9
 Multiple 142.2 1.9
 MW (P value) (0.30) (0.64)

Abbreviations: ASCUS, atypical squamous cells of undetermined significance; HGSIL, high-grade squamous interepithelial lesion; LGSIL, low-grade squamous intraepithelial lesion; MW, Mann-Whitney; UNK, unknown.

∗∗P < 0.01.