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. 2020 Feb 21;11:84. doi: 10.3389/fphar.2020.00084

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Copyright © 2020 Sun, Wang, Zhang, Lu, Duan, Ju, Zhuang and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Eugenol enhanced autophagy in the brains of middle cerebral artery occlusion (MCAO) rats. The expression of LC3 in the cortical penumbra area (A), CA1 hippocampus (B), and striatum (C) was detected by immunofluorescent assay (Scale bar = 50 μm). The expression of Beclin-1 (D), LC3I/II (E), and p62 (F) in brain tissues was assessed by Western blotting. Each experimental datum was presented as mean±standard deviation (n = 6 animals per group). *P < 0.05, **P < 0.01, ***P < 0.001 versus the specified group. ns, no significant difference.