Wei 2003.
Methods | Study design: RCT Conducted in China Number of centres: 1 Recruitment period: unspecified Funding source: unspecified |
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Participants | Inclusion criteria: clinical demonstration of hyperaemic OLP, pathological examination confirmed the diagnosis of OLP, history of OLP for ≥ 3 months Exclusion criteria: OLP did not locate in the buccal mucosa, with other oral mucosa diseases or systematic diseases, first‐onset OLP or history < 3 months, already taking local or systematic therapy in the past 3 months, OLP after the treatment of orthodontics and metallic full crown Group A: randomised 37; analysed 37 Group B: randomised 20; analysed 20 |
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Interventions | Group A: alternative use of mycostatin paste and dexamethasone paste (twice daily each) for 6 weeks Group B: dexamethasone paste (4 times daily) for 6 weeks |
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Outcomes | Clinical score (4‐grade score) | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method of sequence generation not described by translator. |
Allocation concealment (selection bias) | Unclear risk | Insufficient information to permit judgement. |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Quote: "Double blind." |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Quote: "Double blind." |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No missing data. All randomised participants included in analysis. |
Selective reporting (reporting bias) | Unclear risk | Insufficient information to permit judgement. |
Other bias | Low risk | No other sources of bias identified. |