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. 2020 Feb 21;9(1):37–50. doi: 10.1089/biores.2020.0005

FIG. 3.

FIG. 3.

(a) sPLS-DA plot demonstrating discrete cluster separation for metabolomic concentration assessment of cell-based subset group with differentiated (gray) and undifferentiated (black) hMSCs on tissue culture substrates compared to hMSC-seeded (white) scaffolds. (b) Twenty-one metabolites driving separation observed in sPLS-DA plot. (c) sPLS-DA plot demonstrating discrete cluster separation for metabolomic concentration assessment of material-based subset group with dry (white) and media-exposed (gray) scaffolds compared to hMSC-seeded (black) scaffolds. (d) Fifteen metabolites driving separation observed in sPLS-DA plot. hMSC, human mesenchymal stem cell; sPLS-DA, sparse partial least squares discriminant analysis.