Table 4.
The expression of certain long noncoding RNAs during the progression of mammalian spermatogenesis
| LncRNA name | Locationa/Length | Expression level [Ref] |
|---|---|---|
| Gm11837 | Chr.4: 14929908–14953030 (23122 bp) | Highly expressed in adult mouse testis [53] |
| LncRNA-Gm2044 | Chr.7: 139957005–139958039 (1034 bp) | Highly expressed in spermatocytes [78] |
| LncRNA H19 | Chr.7:142575529–142578143 (2.6 kb) | Highly expressed in testis [5] |
| Meiotic recombination hot spot1 locus (Mrhl) | Chr.8:85994245–85996642 (∼2.4 kb) | Expressed in spermatogonial Gc1-Spg (derived from type B spermatogonia) cells [79] |
| AK007004 | Chr.12:82932520–82939155 | Low expressions in male germ cells [80] |
| AK015322 | Chr.12:26814371–26834873 | Highly expressed in spermatogonial stem cells [36] |
| 1700101O22Rik | Chr.12: 7372039–7380330 (8291 bp) | Highly expressed in testicular germ cells in the meiotic prophase and round spermatocyte stage of spermatogenesis [53] |
| lncRNA4667 | Chr.13:23396074–23397418 (1.3 kb) | Highly expressed in round spermatids [55] |
| 1700108J01Rik | Chr.14:122229905–122233638 (3733 bp) | Specifically expressed in testis and highly expressed in testicular germ cells during testicular spermatogenesis [53] |
| LncRNA HOTAIR | Chr.15:102944062–102947730 (∼3.7 kb) | Low processes in the spermatozoa of patients with asthenozoospermia and oligoasthenozoospermia [57] |
| Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) | Chr.19:5795690–5802671 (∼7 kb) | Expressed in sperm cells and intestinal cells of testis [19] |
| LncRNA-Tsx | Chr.X | Expressed in meiotic germ cells [81] |
| LncRNA-Xist (X-inactive specific transcripts) | Chr.X:103460373–103483233 | Highly expressed in male germ cells [81] |
| Tslrn1 (1700019B21Rik) | Chr.X:62510539–62527011 (∼16.5 kb) | Highly expressed in pachytene spermatocytes [54] |
| Tesra | 4435 bp | Highly expressed in the nuclei of pachytene spermatocytes [82] |
| LncRNA-Tcam1 | 2.4 kb | Expressed in mouse male germ cells [55] |
| LncRNA033862 | ∼6.4 kb | Highly expressed in mouse spermat- ogonial stem cells especially in early spermatogonia [80] |
aThe chromosomal location is in the mouse genome