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. 2020 Feb 28;19:45. doi: 10.1186/s12943-020-01163-z

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — CircMUC16-mediated autophagy flux of epithelial ovarian cancer. a CircMUC16 expression was determined in four cell lines by qPCR. b CircMUC16 expression was detected in SKOV3 cells. c The expression of circMUC16 was detected in A2780 cells. d Western blot was used to detect the expression of LC3-II after silencing or ectopic expression of circMUC16. e mRFP-GFP-LC3 distributions in SKOV3 and A2780 cells were analyzed by confocal microscopy after silencing or ectopic expression of circMUC16. The symbols * and ** show p < 0.05 and 0.01, respectively. Scale bar: 5 μm