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Knockdown of hsa_circ_0088732 suppressed glioma growth in vivo. (A,B) Gross glioma tumor samples were taken from nude mice at 21 days after injection of LN229 cells (*P < 0.05, **P < 0.01). (C) qRT-PCR was used to analyze hsa_circ_0088732 and miR-661 expression (**P < 0.01). (D) Representative images of H&E, Ki-67, and Tunel staining assays. (E) Western blot analysis of RAB3D expression. NC: negative control, KD: hsa_circ_0088732 siRNAs, OE: hsa_circ_0088732 overexpression plasmids.
