IgE deficiency reduces atherosclerosis in Apoe−/− mice after 12 weeks of an atherogenic diet. A. En face oil-red O staining and quantifications of the whole aortic tree. B. Intima α-SMC-positive area. C. Intima myosin heavy chain-11-positive area. D. Intima CD31-positive area. Representative images are shown to the left. Scale: 200 μm, inset: 70 μm. E. Plasma total cholesterol, total triglyceride, HDL, and LDL levels. F-G. Distribution of cholesterol (E) and triglyceride (F) in lipoprotein particles based on FPLC lipoprotein profiling. n=6~16 mice per group. All data are mean±SEM. *P<0.05, **P<0.01, ***P<0.001.