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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 Jan 30;40(3):597–610. doi: 10.1161/ATVBAHA.119.313744

Figure 2.

Figure 2.

IgE deficiency reduces aortic arch lesion inflammation in Apoe−/− mice after 12 weeks of an atherogenic diet. Intima major histocompatibility complex class-II (A) and Mac-3-positive macrophage contents (B) were presented as positive area versus total intima area in percentage. C-D. FACS analysis of F4/80+CD11b+ macrophages in peritoneal cavity and blood. E. FACS analysis of Ly6ChiCD11b+ and Ly6ClowCD11b+ monocytes in blood. (F) Intima MCP-1 contents were presented as positive area versus total intima area in percentage. G. Plasma IL-1β, TNF-α, IL-6, IFN-γ and MCP-1 levels. n=6~13 mice per group. Representative images for panels A-F are shown to the left. Scales: 200 μm, insets: 70 μm. All data are mean±SEM. *P<0.05, **P<0.01, ***P<0.001.