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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Aliment Pharmacol Ther. 2020 Jan 21;51(6):652–660. doi: 10.1111/apt.15639

Figure 2. Flow diagram of cirrhosis patients including in our analysis cohort.

Figure 2.

The cohort included patients with at least two ICD-9 codes for cirrhosis with sufficient insurance/pharmacy coverage, a 12 month look-back, no decompensation events during the look-back and no episodes of HE during the 6 months after cirrhosis index date. Our final cohort included 6,451 well-compensated cirrhosis patients who were followed for 6 months to assess their exposure to opioids and then for a further 1 year to assess for the development of incident HE.