Figure 1 –

PEPTIDE methodology. (a) Sampling of EPTI methods in ky-t space (left), demonstrating the segmented zig-zag pattern that allows neighboring data-points to be acquired with minimal time-spacing. This is shown in k_y-k_x-t space for a typical EPTI trajectory (middle), with complete sampling in k_x. The proposed PEPTIDE trajectory (right) with rotation of the EPTI segments in the k_x-k_y plane, to enable motion-robust reconstruction. (b) Applying this trajectory with a combined gradient- and spin-echo sequence, complete reconstruction of k-t space provides time-resolved, distortion and blurring-free T2- and T2*-weighted images for each time point.