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. 2015 Nov 8;2015(11):CD004402. doi: 10.1002/14651858.CD004402.pub3

Comparison 2. Steroid in combination with antiviral drug versus placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Duration of fever. Steroids in combination with acyclovir 1 30 Odds Ratio (M‐H, Fixed, 95% CI) 3.0 [0.68, 13.31]
2 Severe pharyngeal discomfort between 2 and 4 days. Steroids in combination with acyclovir 1 85 Odds Ratio (M‐H, Fixed, 95% CI) 0.31 [0.09, 1.08]
3 Resolution of fatigue at 20 days. Steroids in combination with valacyclovir 1 30 Odds Ratio (M‐H, Fixed, 95% CI) 8.0 [1.52, 42.04]
4 Regain of weight at 14 days 1 79 Odds Ratio (M‐H, Fixed, 95% CI) 0.66 [0.26, 1.66]
5 Selected symptom score improvement 1 30 Odds Ratio (M‐H, Fixed, 95% CI) 9.33 [0.96, 90.94]
6 Total symptom score improvement 1 30 Odds Ratio (M‐H, Fixed, 95% CI) 2.0 [0.38, 10.51]