. 2020 Feb 28;105(3):e782–e790. doi: 10.1210/clinem/dgz313

Table 3.

Rank correlation across the second and third trimesters of participant total urinary glucocorticoid excretion or estimated enzymatic function

	Standardized Coefficient, β
Total urinary glucocorticoids	.387^a
11β-HSD2 activity = F/E	.652^a
11β-HSD total activity = (THF + α-THF)/THE	.352^a
Relative 5β -reductase and 5α -reductase activity = THF/α-THF	.581^a
5α -reductase activity = F/α-THF	.438^a
5β-reductase metabolism of F = F/(THF + α-cortol + β-cortol)	.328^a
5β-reductase metabolism of E = E/(THE + +α-cortolone + β-cortolone)	.608^a

Adjusted according to the gestation of urine collection.

Abbreviations: E, cortisone; F, cortisol; HSD, hydroxysteroid dehydrogenase; HSD2, hydroxysteroid dehydrogenase type 2; THE, tetrahydrocortisone; THF, 5β-tetrahydrocortisol.

^a P less than .001.