Table 3.
Multivariate analyses comparing relative risks for colorectal cancer in relation to folic acid supplement intake, using varying criteria for definition of exposure and inclusion of adjustment variables.
| Sensitivity analysis | Exposed cases/control (n) | OR (95% CI)1 history of folic acid intake vs no intake |
OR (95% CI)1 ≥5 yrs folic acid intake vs no intake |
|---|---|---|---|
| All exposures recorded at least 36 months since diagnosis | 27/61 | 0.81 (0.46 to 1.42) | 1.00 (0.3.7 to 2.65) |
| Restricted analysis to those with full information on adjusting variables | 22/62 | 0.95 (0.51 to 1.79) | 0.81 (0.32 to 2.05) |
1 Adjusted for smoking, body mass index, hypertension, diabetes, GI disorders, Overall P-value >0.05.
Abbreviations: CI, Confidence interval.