Figure 3.
Effects of exendin-4 on GLP-1R expression in the hippocampal dentate gyrus.
Exendin-4 attenuated GLP-1R decrease after nerve injury. (A–D) Expressions are shown by immunofluorescence staining (A, B) and western blot assay (C, D). Western blots are expressed as percentages and fold changes compared with GAPDH (D). (A) Green: GLP-1R; blue: DAPI. Scale bars: 200 µm. *P < 0.05, vs. normal group; #P < 0.05, vs. SNL group (mean ± SEM, n = 6; one-way analysis of variance followed by Bonferroni post hoc test). GLP-1R: Glucagon-like peptide-1 receptor; SNL: spinal nerve ligation.