Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 24;14:731–744. doi: 10.2147/DDDT.S231916

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Hang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

ASK1 inhibition attenuated the expression of NLRP3 inflammasome-related proteins rather than ERS-related proteins in ox-LDL-treated endothelial cells. Ox-LDL-induced endothelial cells were treated with an ASK1 inhibitor (GS-4997). (A) The levels of ASK1 and p-ASK1 expression were examined by Western blotting. (B) The expression of ERS-related proteins was investigated by Western blotting. (C) Western blot analyses of inflammasome-associated proteins. (D) IL-1β and IL-18 levels as detected by ELISA. (E) LDH levels as detected using a LDH-Cytotoxicity Assay Kit. *P < 0.05, **P < 0.01 vs control group; ^#P < 0.05 vs ox-LDL group.