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. 2020 Feb 24;14:745–755. doi: 10.2147/DDDT.S203048

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© 2020 Hua et al.

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Effects of NVP-BSK805 treatments on KYSE-150 and KYSE-150R cell cycle progression. (A) KYSE-150 cells and KYSE-150R cells were pretreated with 10 μM NVP-BSK805 4 h before irradiation (6 Gy). Cell cycle progression was detected by FACS analysis. Cells in G0/G1 were marked in the orange area, purple area for the S cells and red area for the G2/M cells. (B) Cell cycle distribution was calculated with CytoFLEX S, Beckman Coulter. After 6-Gy radiation exposure, the NVP-BSK805 group had the least S phase cell accumulation (7.85%,8.7% in KYSE-150, KYSE-150R cells, respectively).