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. 2020 Feb 18;26:e921502-1–e921502-9. doi: 10.12659/MSM.921502

Figure 3.

Figure 3

CircRNA-0001283 targets miR-187. (A) MiR-187 expression in breast cancer cells were determined by quantitative real-time polymerase chain reaction. (B) MiR-187 expression was decreased following circRNA-0001283 overexpression. (C) Luciferase reporter gene assay in MCF-7 cells overexpressing circRNA-0001283 (wild type/mutant) and miR-187 (NC/mimic). (D) Overexpression of circRNA-0001283 decreased breast cancer cell proliferation induced by miR-187. (E) Overexpression of circRNA-0001283 inhibited breast cancer cell invasion induced by miR-187. * P<0.05, ** P<0.01 versus NC. # P<0.05 versus miR-187 mimic.