Table 2.

Radiology, Infections, and Antimicrobial Therapy in 367 Methicillin-Sensitive Staphylococcus aureus Bacteremia Patients who Survived the First 90 Days; Categorization According to Formal Infectious Diseases Specialist Consultation

	Formal Infectious Diseases Specialist Consultation
Parameters	Present n = 304 (83)	Absent n = 63 (17)	ORs (95% CI)	P
Radiological investigations
Echocardiography
Transthoracic	204 (67)	38 (60)	1.34 (0.77–2.35)	.30
Transesophageal	44 (14)	1 (2)	10.5 (1.42–77.6)	.005
Whole-body computed tomography
≥1 per patient	203 (67)	31 (49)	2.08 (1.12–3.59)	.008
No. per patient, mean ± SD	1.10 ± 1.0	0.49 ± 0.5	—	.004
Magnetic resonance imaging
≥1 per patient	64 (21)	0	—	—
No. per patient, mean ± SD	0.29 ± 0.6	0	—	—
Leukocyte indium-111 scintigraphy	127 (42)	7 (11)	5.74 (2.53–13.0)	<.001
Infection focus and eradication
Pneumonia	112 (37)	11 (17)	2.76 (1.38–5.50)	.003
Endocarditis	40 (13)	2 (3)	4.62 (1.09–19.6)	.023
Osteomyelitis and/or septic arthritis	120 (39)	6 (10)	6.23 (2.60–14.9)	<.001
Any deep infection focus	236 (78)	24 (38)	5.64 (3.17–10.0)	<.001
Eradication of deep infection focusa	83 (27)	0	—	—
Eradication of infected foreign body	34 (11)	0	—	—
Antimicrobial therapy
Antistaphylococcal penicillinb	255 (84)	25 (40)	7.91 (4.38–14.3)	<.001
Cephalosporinec	40 (13)	23 (37)	0.26 (0.14–0.49)	<.001
Other therapyd	9 (3)	15 (24)	0.09 (0.04–0.24)	<.001
Vancomycin	7 (2)	3 (5)	0.47 (0.12–1.88)	.28
Fluoroquinolonee	159 (52)	27 (43)	1.46 (0.85–2.53)	.17
Aminoglycosidee	47 (15)	13 (21)	0.70 (0.36–1.39)	.31
Rifampicine,f	174 (57)	23 (37)	2.33 (1.33–4.08)	.003

Data are No. (%) of patients. Hazard ratios and 95% confidence intervals are presented.

Abbreviations: CI, confidence interval; ORs, odds ratio.

^aSurgical or radiological eradication.

^bCloxacillin.

^cCefuroxime or ceftriaxone.

^dVancomycin, clindamycin, or a carbapenem.

^eAdjunctive antimicrobial therapy.

^fTherapy duration ≥14 days.