Table 2.
No. | Age (yr) | Histological Type | AFP (ng/mL) | CA125 (U/mL) | FIGO Stage | GA Diagnosis | Treatment During Pregnancy | Initial Surgery Time | Initial Surgery Method | Initial Surgery Procedure | GA Delivery (w) | Delivery Route | Pregnancy Outcome | Outcome | OS (mo) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 26 | DG | 119 | 58 | IC2 | 2nd T | Observation | 3rd T | Open | Comb | 37 | CS | Live birth | NED | 32 |
2 | 27 | IT | 82.7 | 140 | IC2 | 2nd T | Observation | 3rd T | Open | Comb | 34+6 | CS | Live birth | NED | 47 |
3 | 29 | IT | 50 | ND | IA | 1st T | Surgery | 2nd T | Lap | USO | 40 | VD | Live birth | NED | 41 |
4 | 28 | IT | 1.8 | 8.8 | IA | 1st T | ET, surgery | 1st T | Open | USO | ND | ND | ET | NED | 50 |
5 | 32 | IT | ND | 117 | IC1 | 1st T | ET, surgery | 1st T | Lap | Cys | ND | ND | ET | NED | 86 |
6 | 29 | YST | 12,830 | 412 | IC2 | 1st T | Surgery+chemo | 2nd T | Open | USO | ND | ND | ETc | NED | 68 |
7 | 26 | YST | >1000 | ND | IC2 | 1st T | Surgery+chemoa | 2nd T | Open | USO | 35 | CS | Premature death | NED | 80 |
8 | 30 | YST | >1000 | ND | IA | 1st T | Surgery | 2nd T | Lap | Cys | 39+5 | VD | Live birth | NED | 23 |
9 | 24 | YST | 32,825 | 261 | IC2 | 1st T | ET, surgery | 2nd T | Open | USO | ND | ND | ET | NED | 52 |
10 | 18 | YST | 6780 | 178 | IIIA | 1st T | ET, surgery | 1st T | Open | Comb | ND | ND | ET | NED | 23 |
11 | 27 | YST | 80,500 | 256 | IIIC | 2nd T | Chemo | 3rd T | Open | CRS | 35 | CS | Live birth | DOD | 40 |
12 | 34 | Mixed | 174 | 702 | IIIC | 3rd T | No treatment | 3rd T | Open | Comb | 36 | CS | Live birth | DOD | 20 |
13 | 30 | Mixed | 142.3 | ND | IC1 | 1st T | Surgery+chemo | 2nd T | Lap | USO | ND | ND | ETc | NED | 13 |
14 | 23 | Mixed | 19.1 | 58.4 | IC2 | 1st T | Surgery | 2nd T | Open | USO | 37 | CS | Live birth | NED | 64 |
Notes: aThe patient accepted one cycle of chemotherapy after recurrence. bFertility-sparing surgery and comprehensive staging, including unilateral salpingo-oophorectomy, omentectomy, pelvic lymphadenectomy. cThe patient chose elective termination after one cycle of chemotherapy in gestation.
Abbreviations: AFP, alpha fetoprotein; Chemo, chemotherapy; Com, comprehensive staging surgery; CRS, cytoreduction surgery; CS, Cesarean section; Cys, cystectomy; DG, dysgerminoma; DOD, dead of disease; ET, elective termination; FIGO, International Federation of Gynecology and Obstetrics; GA, gestation age; IT, immature teratoma; Lap, laparoscopy; ND, not determined; NED, no evidence of disease; OS, overall survival; T, trimester; USO, unilateral salpingo-oophorectomy; VD, vaginal delivery; YST, yolk sac tumor.