Table 3.
Factors Associated with Fatigue
| Author/Year | Number of Participants | Body Mass Index | Co-morbidities | Physical Activity | Depression | Social Support | Sleep | Education Level | Design | Fatigue Measure | Strengths | Weaknesses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ali & Taha, 2017 | 105 | N/A | N/A | N/A | No | N/A | Yes (sleep latency – ↑ fatigue) | No | Descriptive Cross-sectional |
Fatigue Severity Scale | Large sample size of patients on HD | Cross-sectional |
| Bai et al., 2015 | 193 | N/A | No | Yes – (↓) | Depression – (↑) | Yes (No spouse – ↑ fatigue) | N/A | N/A | Descriptive Correlational | Fatigue Scale for hemodialysis patients | Participants recruited from six HD centers | Cross-sectional |
| Bossola, Luciani, & Tazza, 2009 | 62 | N/A | Yes – (↑) | N/A | Depression – (↑) | N/A | N/A | N/A | Cross-sectional | SF-36 | Comparison of fatigue and non-fatigued participants on HD | Limited sample size Cross-sectional |
| Bossola, Stasio, Antocicco, & Tazza, 2013 | 68 | Yes – (↓) | Yes – (↓) | N/A | Depression – (↓) | N/A | N/A | N/A | Cross-sectional | Six Yes or No questions based Hardy and Studenski model | None of the patients on HD were on antidepressants | Dichotomous fatigue measure Limited sample size Cross-sectional |
| Chilcot et al., 2015 | 174 | Yes – (↑) | Yes – (↑) | Yes – (↓) | N/A | No (marital status does not impact fatigue) | N/A | N/A | Cross-sectional | Chalder Fatigue Questionnaire (primary outcome) The Work and Social Adjustment Scale (secondary outcome) |
Measured fatigue severity and fatigue related functional impairment in individuals on HD | Cross-sectional |
| Jhamb et al., 2009 | 917 (705 included in adjusted models) | Yes – (↑) | Yes – (↑) | Yes – (↓) | N/A | N/A | Yes (↓) | N/A | Longitudinal | SF-36 vitality scale | Large sample size Included patients on HD and PD Longitudinal |
Fatigue was only measured at baseline and 1 year on dialysis through vitality scores |
| Karadag,Kilic, & Metin, 2013 | 73 | N/A | N/A | N/A | N/A | Social support – ↓ fatigue | N/A | N/A | Descriptive Cross-sectional |
Fatigue Severity Scale | Compared association of fatigue in individuals on HD with support from family, friends, special person, and overall | Cross-sectional Correlational analysis determined relationship between fatigue, effects may be bidirectional |
| Liu, 2006 | 119 | N/A | N/A | N/A | Depression – (↓) | N/A | N/A | No | Cross-sectional Correlational |
Fatigue Assess Scale | Large sample size of individuals on HD | All patients were married Cross-sectional |
| Wang et al., 2016 | 345 | No | Yes | Yes – (↑) | N/A | No | N/A | No | Cross-sectional | FACIT-Fatigue | Participants recruited from two HD centers Large sample size |
Cross-sectional Only examined a few potential variables for fatigue |
| Zyga et al., 2015 | 129 | N/A | N/A | N/A | N/A | N/A | N/A | Yes – education | Cross-sectional | Fatigue Assessment Scale | Participants recruited from two HD centers Large sample size |
Cross-sectional Physicians, nurses, and other health care providers were present during survey administration |