FIG 1.

Global layout scheme for a consolidated clinical microbiology laboratory organization. The central laboratory comprises, among others, a clinical microbiology unit harboring all key technological facilities, including high-tech facilities for molecular testing, MALDI-TOF MS, and NGS, as well as cell culture laboratory for virus and intracellular bacteria detection and one or more National Reference Laboratories (NRL). At the management level (right part), there are opportunities for reaching out to external specialized facilities (WHONET, ECDC, etc.) as well as all the required IT and informatics facilities. On the left, the satellite laboratories are depicted. These can vary in number and complexity but should be within relatively close proximity and focused on rapid response technology only. (Adapted from reference 18.)