Table 5.

Estimated additional costs of broad-spectrum antibiotic prescription in ambulatory care (unit = million USD)^a

Class	2013	2014	2015	2016
Third-generation cephalosporins	134·7 (132·0–137·5)	114·1 (111·9–116·3)	113·8 (111·5–116·1)	93·7 (91·7–95·7)
Macrolides	133·8 (130·6–137·1)	101·7 (99·3–104·1)	108·1 (105·6–110·5)	93·4 (91·2–95·6)
Fluoroquinolones	135·4 (131·2–139·7)	108·1 (104·9–111·4)	111·2 (107·9–114·6)	93·5 (90·6–96·5)
Total	403·9 (394·8–414·3)	323·9 (316·1–331·8)	333·1 (325·0–341·2)	280·0 (273·5–287·8)

^a Values in parentheses represent 95% confidence intervals