Skip to main content
. 2020 Feb 28;20:52. doi: 10.1186/s12871-020-00969-0

Table 1.

Characteristics of included randomized controlled studies

Author /Year Group(n) Types of surgery Surgical approach TAP block technique Catheter site Local anesthetic administered for TAP block Local anesthetic administered for Epidural analgesia Anesthetic strategy Additional NSAIDs drugs for TAP block Postoperative opioid analgesia required
Kadam 2013 [23] TAP group(22) EA group(19) Colorectal Upper gastrointestinal Urological laparotomy US-guided, single injection followed by continuous infusion Bilateral Posterior 0.375% ropivacaine 20 ml single-injection bilaterally, followed by 0.2% ropivacaine at 8 mL/h through each catheter for 72 h 0.2% ropivacaine(8-15 ml) bolus followed by 0.2% ropivacaine at 5–15 ml/h GA paracetamol 1.0 g every 8 h PCA using fentanyl 10 to 40 μg bolus per press with a lockout time of 6 min and no basal infusion
Niraj 2011 [22] TAP group(27) EA group(31)

Partial hepatectomy

Pancreatic surgery

Radical nephrectomy

Biliary bypass

laparotomy US-guided, single injection followed by continuous infusion Bilateral Subcostal 0.375% bupivacaine (1 mg/kg) single-injection bilaterally, followed a bolus of 0.375% bupivacaine(1 mg/kg) very 8 h through each catheter for 72 h 0.25% bupivacaine(20 ml) followed by 0.125% bupivacaine with 2 μg/ml Fentanyl at 6-12 mL/h for 72 h (2 ml bolus, lockout 30mins) GA paracetamol 1 g every 6 h intravenous tramadol as required
Niraj 2014 [13] TAP group(30) EA group(31)

Right hemicolectomy

Left hemicolectomy

Anterior resection

Sigmoid colectomy

Ileocolic resection

laparoscope US-guided, single injection followed by continuous infusion Bilateral Posterior 0.375% levobupivacaine (1.25 mg/kg)single-injection bilaterally,followed by 0.25% levobupivacaine at 8–10 mL/h through both catheters for 72 h 0.25% Bupivacaine 20 mL followed by 0.125% bupivacaine with 2 μg/mL fentanyl at 8–12 mL/h (2 ml bolus, lockout 30mins) GA paracetamol 1 g every 6 h, diclofenac 150 mg/day intravenous tramadol as required
Ganapathy 2015 [25] TAP group(26) EA group(24)

Small bowel surgery

Large bowel surgery

Ostomy reversal

Whipples’operation

laparotomy US-guided, single injection followed by continuous infusion Bilateral Subcostal Inferior 0.2% ropivacaine 30 ml single-injection bilaterally followed by 0.35% ropivacaineat 4–5 ml/h for 72 h 0.25% bupivacaine 5 ml followed by 0.1% bupivacaine with hydromorphone(10 mg/mL) at 8 ml/h for 72 h GA naproxen 500 mg twice daily, paracetamol 650 mg every 6 h PCA using hydromorphone 0.2 mg bolus per press with a lockout time of 6 min and no basal infusion
Lyer 2017 [27] TAP group(33) EA group(36) lower abdominal surgery laparotomy US-guided, single injection followed by continuous infusion Bilateral Posterior 0.125% bupivacaine 20 ml single-injection bilaterally followed by 15 ml bolus every 8 h through each catheter for 48 h 0.125% bupivacaine 10 ml followed by 0.125% bupivacaine 10 ml every 8 h for 48 h GA Paracetamol 1 g was given to patients if their VAS scores were > 3/10 intravenous tramadol as required
Qin 2016 [26] TAP group(35) EA group(36) laparoscopic colorectal surgery laparoscope US-guided, single injection followed by continuous infusion Bilateral Posterior 0.375% ropivacaine 1.25 mg/kg single-injection bilaterally followed by 0.2% ropivacaine at 6–8 ml/h through both catheters for 48 h 0.375% ropivacaine 10 ml followed by 0.15% ropivacaine with fentanyl 2 μg/ml at 3–6 mL/h for 48 h (3 ml bolus, lockout 15mins) GA / Intravenous tramadol as required
Wahba 2014 [24] TAP group(22) EA group(22) Large bowel surgery Small bowel surgery Gastrectomy Abdominal Hernia laparotomy US-guided, single injection followed by continuous infusion Bilateral Subcostal 0.25% bupivacaine 20 ml single-injection bilaterally followed by 15 ml bolus every 8 h through each catheter for 48 h 0.125% bupivacaine 10 ml followed by 0.125% bupivacaine at 6–8 ml/h for 48 h GA / PCA 1 mg morphine bolus per press with a lockout interval of 10 min
Dai 2017 [15] TAP group(27) EA group(30) laparoscopic colorectal surgery laparoscope US-guided, single injection followed by continuous infusion Bilateral Posterior 0.375% ropivacaine 0.15 ml/kg single-injection bilaterally followed by 0.2% ropivacaine at 0.1 ml/kg/h through both catheters for 48 h 0.375% ropivacaine 8-10 ml followed by 0.15% ropivacaine at a 3–4 ml/h for 48 h (3 ml bolus, lockout 15mins) GA / intravenous tramadol as required

IV intravenous, PCA patient controlled analgesia, TAP transverse abdominis plane, US ultrasound, GA General anesthesia