Fig. 7.

FKBP9 expression resists to ER stress inducer-triggered cell death. a Cell viability of SF-539-FKBP9 and T98G-FKBP9 cells exposed to Tg (0.2 μM) or Tm (1.2 μM) for 24, 48 and 72 h were measured by Cell Counting Kit-8. b Analysis of colony formation of SF-539-FKBP9 and T98G-FKBP9 cells treated with vehicle and 0.1 μM Tg for 12 days. c SF-539-PCDH-vector and SF-539-FKBP9-WT cells were pretreated with Tg (0.5 μM) for 6 h, then implanted into CAM (5 eggs for each). Representative images for tumors after 7 days were shown. d IB analysis for Caspase-12 and CHOP expression in SF-539-FKBP9-WT and T98G-FKBP9-WT cells exposed with Tg for 12 h. The ratios of Cleaved-Caspase-12 and CHOP expression to their corresponding GAPDH were represented. Data are represented as mean ± SEM from three independent experiments, *p < 0.05, **p < 0.01, ***p < 0.001