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. 2020 Feb 18;14(2):e0008044. doi: 10.1371/journal.pntd.0008044

Fig 4. Evaluation of the TevRPA-LF as a test-of-cure tool in T. evansi infections in mice.

Fig 4

A: C57BL/6 mice were infected with T. evansi RoTat1.2 (n = 5) and the presence of parasites was monitored over the course of the infection by microscopy (top panel), the TevPCR (middle panel, performed on parasite genomic DNA purified from the collected blood samples), and TevRPA-LF (bottom panel, executed on crude parasite genomic DNA extracted from the collected blood). The results are displayed as the percentages of mice that scored positive or negative as determined by the above-mentioned techniques. B: C57BL/6 mice infected with T. evansi RoTat1.2 (n = 5) were treated with Berenil at 5 days post-infection. The presence of parasites was followed by microscopy, the TevPCR and the TevRPA-LF throughout the experiment. The panels and color codes are the same as for panel A. The TevPCR and TevRPA-LF read-outs are shown in Fig 5.