Table 2. HHpred analysis of 80α baseplate protein sequences.

The most relevant hits are shown for each protein, with matched residues, PDB ID and chain identifier, HHpred probability (%), E-value and percent sequence identity in matched region.

	Residues	Match	PDB ID	Probability (%)	E-value	Sequence Identity (%)
gp53 (MTP)	1–181	Bacillus siphophage SPP1 gp17.1	5A21_H	99.95	2.50E-30	22
	2–142	Enterobacteria siphophage λ gpV	2K4Q_A	98.85	4.90E-10	10
	2–137	Bacillus subtilis phage-like element PBSX protein xkdM	2GUJ_A	94.41	4.30E-01	10
	61–134	Acinetobacter baumannii T6SS protein Hcp1	4W64_C	67.45	6.00E+01	5
	65–134	Pseudomonas aeruginosa Hcp1 secretion island I protein Hcp1	1Y12_A	52.84	1.20E+02	9
gp56 (TMP)	9–181	Homo sapiens nuclear pore complex protein Nup155	5IJO_M	95.26	2.20E-02	11
	355–466	Human coronavirus spike glycoprotein	5YL9_A	83.93	3.10E+01	15
gp58 (Dit)	1–313	Bacillus siphophage SPP1 distal tail protein (gp19.1)	2X8K_A	99.90	3.80E-25	16
	6–315	Lactococcus siphophage TP901-1 distal tail protein	4V96_AS	99.81	5.70E-21	11
	2–297	Lactococcus siphophage p2 distal tail protein (ORF15)	2WZP_Q	99.34	1.60E-12	8
gp59 (Tal)	1–350	Listeria monocytogenes EGD-e prophage A118 gp18	3GS9_A	100.0	1.70E-33	19
	1–331	Shewanella oneidensis prophage MuSo2 tail protein	3CDD_E	99.06	4.70E-10	11
	9–330	Neisseria meningitidis prophage tail protein	3D37_A	98.97	3.60E-09	10
	1–330	Enterobacteria phage Mu tail protein	1WRU_A	98.93	3.10E-09	12
	16–329	Escherichia coli T6SS protein c3393	2P5Z_X	96.92	4.60E-02	11
	398–631	Bacteroides thetaiotaomicron putative lipase	3BZW_A	99.67	4.30E-18	18
	419–633	Pseudoalteromonas sp. GDSL-esterase	3HP4_A	99.66	6.60E-18	13
	420–628	Streptomyces rimosus SGNH hydrolase	5MAL_B	99.66	6.50E-18	14
gp61 (RBP)	1–636	Staphylococcus phage Φ11 RBP	5EFV_A	100.0	1.30E-125	97
gp62 (FibL)	12–205	Lactococcus phage TP901-1 BppU (ORF48)	4V96_AM	99.70	2.40E-18	15
	149–279	Homo sapiens nuclear pore complex Nup155	5IJN_T	93.80	2.50E-01	10
	401–488	Staphylococcus phage Φ11 RBP	5EFV_A	80.1	7.3E+01	15
	427–490	Pseudomonas aeruginosa (PAO1) R2 pyocin tail fiber	6CU2_A	41.9	1.40E+02	14
	387–607	Staphylococcus phage K putative RBP tower domain	5M9F_A	99.15	6.90E-12	16
gp67 (Hyd)	11–178	Streptococcus pyogenes MGAS5005 phage-associated cell wall hydrolase	5UDN_A	99.70	5.90E-19	20
	209–356	Streptococcus pneumoniae serotype 4 autolysin	5CTV_A	99.29	8.70E-14	10
	406–632	Clostridium perfringens strain 13 N-acetylglucosaminidase	5WQW_A	100.0	2.40E-42	33
gp68 (FibU)	3–168	Lactococcus phage TP901-1 BppU (ORF48)	4V96_AM	99.57	6.40E-16	11
	178–208	Synthetic collagen heterotrimer	5YAN_E	95.36	5.40E-03	44