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Effects of viral infection on cell death. TUNEL staining of E12 eyes infected at stage 10 by RCAS virus (A, C, same section) or Six3 virus (B, D, same section) are shown. Arrowheads point to detected apoptotic cells. Staining with the anti-viral GAG antibody 3C2 (C, D) demonstrates extensive infection of anterior segments by both RCAS and Six3 viruses. Scale bars, 100 μm. Abbreviations: cb, ciliary body; cor, cornea; ir, iris; le, lens.
