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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Neurobiol Learn Mem. 2019 Dec 9;167:107132. doi: 10.1016/j.nlm.2019.107132

Figure 3. Long-delay fear conditioning increases lateral amygdala neuronal excitability in a time-dependent manner.

Figure 3.

(A) Representative traces illustrating spike frequency adaptation in response to a prolonged current injection in neurons from control and fear conditioned rats studied either 1-hr or 24-hr later. Note that LA pyramidal neurons from Control rats (n = 28) but not Conditioned-24hr rats (n = 28) display robust spike frequency adaptation. Scale bar, 20 mV, 200 ms. (B) Bar graphs illustrating the average number of APs elicited during prolonged current injection. LA pyramidal neurons from Conditioned-24hr rats fire significantly more APs than those from Control rats. Neurons from Conditioned-1hr rats (n = 13) are not significantly different from any other group. Asterisk (*) indicates p < 0.05 relative to LA neurons from Control rats. Abbreviations: lateral amygdala (LA); action potential (AP). Adapted from Sehgal et al., 2014.