Table 1:
Correlations between region-specific brain damage in neurologic WD and accompanying neurologic symptomsa
| Neurologic Symptoms | No. of Cases | Putamen | Globus Pallidus | Caudate Nucleus | Thalamus | Midbrain | Pons | Cerebellum | Frontal Lobe | Temporal Lobe | Parietal Lobe | Corpus Callosum |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dystonia | 197 | 159 (80.7) | 34 (17.3) | 66 (33.5) | 73 (37.1) | 67 (34.0) | 95 (48.2) | 4 (2.0) | 4 (2.0) | 3 (1.5) | 3 (1.5) | |
| Parkinsonism | 127 | 104 (81.9) | 19 (15.0) | 41 (32.3) | 45 (35.4) | 31 (15.7) | 52 (26.4) | 4 (3.1) | 3 (2.4) | 3 (2.4) | 6 (4.7) | |
| Torsion spasm | 32 | 25 (78.1) | 2 (6.3) | 10 (31.2) | 8 (25) | 18 (56.3) | 20 (62.5) | 7 (21.9) | 6 (18.8) | 6 (18.8) | 2 (6.3) | |
| Choreoathetosis | 8 | 7 (87.5) | 1 (12.5) | 8 (100) | 5 (62.5) | 6 (75) | 2 (25) | |||||
| All patients | 364 | 295 (81.0) | 56 (15.4) | 125 (34.3) | 131 (36.0) | 122 (33.5) | 169 (46.4) | 8 (2.2) | 11 (3.2) | 12 (3.3) | 12 (3.3) | 8 (2.2) |
a
Data are number and percentage.