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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Hepatology. 2020 Jan 24;71(4):1228–1246. doi: 10.1002/hep.30921

Figure 3. ATAC-seq analysis of liver chromatin accessibility.

Figure 3.

ATAC-seq was performed on liver nuclei isolated from Ctrl (n=6) and LKO (n=6) mice after six months of HFD feeding.

(A) Pie chart showing ATAC-seq peaks altered by hnRNPU deficiency.

(B) Heat map representation of peaks increased or decreased by over 2-fold in hnRNPU LKO mouse livers.

(C) UCSC genome browser tracks near Ntrk2 and Cyp4a10.

(D) Motif-enrichment analysis of the upregulated and downregulated ATAC-seq peaks.