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. 2020 Feb 28;40(2):BSR20200041. doi: 10.1042/BSR20200041

Figure 3. SLC39A7 affects GC cells proliferation, migration and apoptosis through Akt/mTOR pathway.

Figure 3

HGC-27 cells were transfected with si-RNA or si-SLC39A7 and treated with SC79 or MHY1485. pS473-Akt/Akt (A,C) and p-mTOR/mTOR (B,C) protein expression in HGC-27 cells was assessed by Western blot. (D) MTT assay, (E) wound-healing assay and (F) apoptosis assay were recruited to analyze the proliferation, migration and apoptosis of HGC-27 cells with si-SLC39A7 or si-RNA transfection and SC79 or MHY1485 treatment. ##P<0.01 vs si-RNA and &&P<0.01 vs si-SLC39A7.