Table 2.
Survival analysis of DFS according to clinicopathologic variables.
| Characteristics | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR | p value | HR | p value | |
| Age, years |
0.979 (0.950, 1.008) |
0.158 | ||
| Tumor size on MRI (mm) |
1.023 (1.008, 1.039) |
0.003 |
0.993 (0.972, 1.015) |
0.532 |
| Pathological T category | ||||
| pT1 | ||||
| pT2 |
2.749 (1.341, 5.637) |
0.006 |
1.812 (0.775, 4.240) |
0.170 |
| pT3 |
2.901 (0.659, 12.78) |
0.159 |
1.529 (0.316, 7.391) |
0.597 |
| Pathological N category | ||||
| pN0 | ||||
| pN1 |
6.416 (2.826, 14.56) |
<0.001 |
2.906 (1.080, 7.821) |
0.035 |
| pN2 |
16.984 (6.977, 41.34) |
<0.001 |
6.622 (2.099, 20.887) |
0.001 |
| Type of surgery | ||||
| Breast-conserving surgery | ||||
| Mastectomy |
3.873 (1.892, 7.926) |
<0.001 |
2.281 (0.963, 5.402) |
0.061 |
| Adjuvant radiation therapy | ||||
| No | ||||
| Yes |
1.211 (0.466, 3.146) |
0.694 | ||
| Neoadjuvant chemotherapy | ||||
| No | ||||
| Yes |
5.231 (2.575, 10.63) |
<0.001 |
1.320 (0.267, 6.528) |
0.733 |
| Adjuvant chemotherapy | ||||
| No | ||||
| Yes |
0.220 (0.106, 0.456) |
<0.001 |
0.364 (0.077, 1.719) |
0.202 |
| Histological grade | ||||
| 1 or 2 | ||||
| 3 |
1.321 (0.626, 2.791) |
0.465 | ||
| Lymphovascular invasion | ||||
| No | ||||
| Yes |
10.195 (4.881, 21.29) |
<0.001 |
2.566 (1.018, 6.469) |
0.046 |