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. 2020 Feb 28;5:17. doi: 10.1038/s41541-020-0166-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a ELISA assays and b neutralization assays were performed on serum samples from all vaccine recipients. The ELISA endpoint titer is the dilution of serum at which the signal was three standard deviations above that of the average of the negative controls. The mean and standard deviation of technical replicates is shown. The focus reduction neutralization titer 50 (FRNT₅₀) is the dilution of the serum that neutralized 50% of the input foci. A human serum control is also shown for the neutralization assay since low-level, non-specific neutralization can be seen in this sample.