Fig. 2. Mapping RVFV-specific T cell epitopes in vaccine recipients.

a A graphical depiction of each viral structural protein (N, Gn, and Gc), with a heatmap to indicate the number of donors whose PBMCs recognized the epitope based upon individual peptide assays performed by ELISPOT. The magnitude and amino acid location for all positive donors for the three structural proteins: b N, c Gn, and d Gc. e Experimentally determined epitopes correlate well with bioinformatic prediction of epitopes recognized by the common human allele reference set.