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. 2020 Feb 28;11:1122. doi: 10.1038/s41467-020-14843-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Manhattan plot of the GWAS meta-analysis. The black dotted line denotes the genome-wide significance threshold (p-value < 5e-8) while the red dotted line denotes the suggestive threshold (p-value < 1e-6). N = 448,549 independent participants. b Genetic correlation values between heart failure and other complex traits. The x-axis shows the genetic correlation r-value. Traits are color coded based on the group in which they belong. Stars denote the Bonferroni adjusted z-test p-value: (*) 0.001 < p-value < 0.01, (**) 0.0001 < p-value < 0.001, (***) p-value < 0.0001. N = 1,171,562 SNPs. Source data are provided as a Source Data file.