Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 28;3:86. doi: 10.1038/s42003-020-0815-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Example images of white-to-opaque sector-based switching (left) and adjacent white and opaque colonies (right). b Phase-contract microscopy images of white and opaque cells at ×1000 magnification. c Quantification of white-to-opaque switching under standard conditions and after UV-treatment; N = 3 independent experiments. An example of untreated and UV-treated cells are shown on the right, with opaque sectors denoted by arrows. d DNA content analysis of white, opaque, and ten opaque cell derivatives (including a white cell revertant, Iso 14), as measured by flow cytometry. e Example image of reverse switching of an opaque colony (left), and colonies derived from re-plating the same colony (right). f CHEF gel analysis of chromosome banding pattern of white, opaque, and ten opaque cell derivatives (including a white cell revertant, Iso 14). S. cerevisiae BY4742 denotes size standards. Error bars represent the standard deviation of the mean; significance values are shown in Supplementary Data 1.