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SLX41–758–XPF–ERCC1 mutation data summary.
| Protein | Mutant | Vmax (fmol min−1) | Km (nM) | kcat (min−1) | kcat/Km (nM−1 min−1) |
|---|---|---|---|---|---|
| XPF(–ERCC1–SLX4NTD) | WT | 219.2 ± 9.3 | 4.2 ± 0.7 | 43.8 ± 1.1 | 10.4 |
| XPF(–ERCC1–SLX4NTD) | 323–326 Δ | 49 ± 6.5 | 32.2 ± 9.6 | 9.8 ± 1.4 | 0.30 |
| XPF(–ERCC1) | WT | 104.7 ± 2.8 | 12.1 ± 1.4 | 20.9 ± 0.66 | 1.73 |
Each kinetic value was obtained from 3 technical replicates (n = 3) ± the standard deviation (SD).
