Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 28;11:1126. doi: 10.1038/s41467-020-14963-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 8 — a Workflow for treatment of EMT6-bearing mice using PTT-based neutrophil-mediated NPNs@Pt delivery system. On day -1 and day 2 (defined as the 7th and 10th day after tumor inoculation, respectively), mice were i.v. injected with NPs@PBT. On days 0 and 3, the mice received PTT treatment on the tumors followed by an i.v. injection of PBS, NPs@Pt, or NPNs@Pt. Tumor volumes were measured every two days from day 0 to day 20. n = 6 for PTT + NPNs@Pt, and n = 5 for the other groups. b Tumor growth curves during the treatments. c–g Growth of individual tumors during the treatments. h The percentage of tumor-free mice during the treatments. i Change of mouse weight during the treatments. j Photos of mice treated with PTT + NPNs@Pt on day 20, which showed complete eradication of the EMT6 tumors in all six mice. k Photos and l weight of the tumors collected on day 20. Data are shown as mean ± SEM and analyzed by unpaired two-tailed Student’s t-test. ***P < 0.001, ****P < 0.0001. N.D. not detected. Source data are provided as a Source Data file.