Table 2.
Baseline characteristics of patients with type 2 diabetes who were hospitalized for Fournier’s gangrene (cases) and matched controls at the index date of FG diagnosis
| Characteristics | Cases | Controls |
|---|---|---|
| N | 216 | 1296 |
| Male, n (%) | 201 (93.1) | 1206 (93.1) |
| Age, mean ± SD | 56.2 ± 10.9 | 56.4 ± 10.5 |
| Duration of follow-up (days), mean ± SD | 774.6 ± 506.5 | 774.7 ± 506.8 |
| Hypertension, n (%) | 137 (63.4) | 771 (59.5) |
| Obesity, n (%)** | 62 (28.7) | 195 (15.0) |
| Insulin use, n (%)** | 84 (38.9) | 228 (17.6) |
| Coronary heart disease, n (%)* | 39 (18.1) | 157 (12.1) |
| Congestive heart failure, (n (%)** | 31 (14.4) | 42 (3.2) |
| Peripheral artery disease, n (%)** | 27 (12.5) | 52 (4.0) |
| Stroke, n (%) | 4 (1.9) | 21 (1.6) |
| Lower extremity amputation, n (%) | 2 (1.0) | 4 (0.3) |
| Diabetic ketoacidosis, n (%)* | 4 (1.9) | 3 (0.2) |
| Diabetic neuropathy, n (%)** | 39 (18.1) | 111 (8.6) |
| Diabetic retinopathy, n (%)* | 15 (6.9) | 44 (3.4) |
| Pancreatitis, n (%)* | 6 (2.8) | 6 (0.5) |
| Moderate to severe renal insufficiency/diabetic nephropathy, n (%)** | 40 (18.5) | 92 (7.1) |
| Charlson comorbidity index, n (%)** | ||
| 0 | 1 (0.5) | 211 (16.3) |
| 1 | 73 (33.8) | 675 (52.1) |
| ≥ 2 | 142 (65.7) | 410 (31.6) |
| ≥ 6 of non-diabetic medications, n (%)* | 130 (60.2) | 579 (44.7) |
| No. of non-insulin antidiabetic medications, n (%)** | ||
| 0 | 75 (34.7) | 236 (18.2) |
| 1 | 76 (35.2) | 624 (48.2) |
| ≥ 2 | 65 (30.1) | 436 (33.6) |
| Prior hospitalizations, n (%)** | 53 (24.5) | 70 (5.5) |
SD standard deviation
*p < 0.05 for difference between cases and controls; **p < 0.001 for difference between cases and controls