Table 5. The top 10 miRNAs upregulated in SD or PD tissue compared to PR tissue.
| Gene symbol | FPKM (mean ± SD) | Mean fold change (SD or PD/PR, ± SD) | P valuea | |
|---|---|---|---|---|
| SD or PD | PR | |||
| hsa-miRNA 601 | 1.57±0.32 | 1.64±0.50 | 6.24±0.61 | 1.18×10−19 |
| hsa-miRNA 596 | 0.93±0.56 | 1.05±0.54 | 6.21±0.79 | 1.62×10−15 |
| hsa-miR-615-5p | 1.78±0.46 | 0.95±0.61 | 6.08±0.75 | 4.29×10−16 |
| hsa-miR-224-5p | 1.75±0.24 | 0.91±0.56 | 6.07±0.61 | 1.44×10−20 |
| hsa-miR-6718-5p | 1.37±0.48 | 0.57±0.55 | 6.15±0.72 | 2.87×10−19 |
| hsa-miR-3616-3p | 2.11±0.64 | 1.32±0.78 | 6.11±0.95 | 8.07×10−13 |
| hsa-miR-504-5p | 1.32±0.29 | 0.54±0.49 | 6.01±0.57 | 2.29×10−23 |
| hsa-miR-3180-5p | 1.72±0.30 | 0.94±0.65 | 5.96±0.71 | 2.68×10−16 |
| hsa-miR-4802-3p | 1.64±0.23 | 1.65±0.63 | 5.73±0.58 | 3.01×10−20 |
| hsa-miR-1260a | 2.13±1.02 | 1.05±0.95 | 5.10±1.40 | 3.34×10−6 |
a, P values were calculated by the paired t-test. SD, standard deviation; PR, partial response; SD, stable disease; PD, progressive disease; FPKM, fragments per kilobase of exon per million fragments mapped.