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. 2020 Feb;8(4):121. doi: 10.21037/atm.2020.01.75

Table S4. The top 10 genes upregulated in ED stage tissue compared to LD stage tissue.

Gene symbol FPKM (mean ± SD) Mean fold change (ED/LD, ± SD) P valuea
ED LD
KRT6A 2.28±1.29 0.18±0.16 127.76±1.30 5.905×10−11
KRT5 2.28±0.95 0.23±0.41 57.09±1.03 3.40×10−12
KRT17 1.63±0.96 0.12±0.18 32.56±0.98 5.00×10−11
AC008870.1 1.61±0.93 0.19±0.14 26.60±0.84 4.79×10−12
KRT16 1.61±0.93 0.31±0.24 20.28±0.96 8.58×10−10
AC091564.5 1.96±0.65 0.71±0.46 18.06±0.80 1.08×10−13
LINC00498 1.28±0.65 0.05±0.13 17.22±0.95 4.15×10−9
AC009137.2 1.21±0.79 0.02±0.02 15.60±0.79 3.20×10−10
AC121247.1 1.57±0.80 0.39±0.35 15.25±0.88 2.88×10−9
DAPK1-IT1 1.52±0.89 0.35±0.34 14.67±0.95 1.20×10−8

a, P values were calculated by the paired t-test. ED, extensive disease; LD, limited disease; FPKM, fragments per kilobase of exon per million fragments mapped; SD, standard deviation.