Table S6. miRNAs with >4-fold downregulated expression in SD or PD tissue compared to PR tissue.
| Gene symbol | FPKM (mean ± SD) | Mean fold change (PR/SD or PD, ± SD) | P valuea | ||
|---|---|---|---|---|---|
| SD or PD | PR | ||||
| hsa-miR-6073 | 1.43±0.63 | 2.19±0.30 | 5.70±0.70 | 2.28×10−17 | |
| hsa-miR-3152-5p | 1.95±0.87 | 2.70±0.13 | 5.58±0.88 | 8.00×10−12 | |
| hsa-miR-4652-5p | 1.04±0.70 | 1.77±0.67 | 5.46±0.97 | 1.89×10−10 | |
| hsa-miR-3162-3p | 1.02±0.50 | 1.76±0.28 | 5.41±0.57 | 2.54×10−22 | |
| hsa-miR-3607-5p | 0.91±0.60 | 1.64±0.31 | 5.37±0.67 | 6.77×10−17 | |
| hsa-miR-135a-3p | 0.70±0.45 | 1.43±0.24 | 5.35±0.51 | 1.26×10−21 | |
| hsa-miR-3617-5p | 1.59±0.88 | 2.31±0.44 | 5.24±0.99 | 8.02×10−11 | |
| hsa-miR-758-5p | 0.92±0.60 | 1.64±0.30 | 5.23±0.66 | 2.76×10−17 | |
| hsa-miR-4301 | 0.43±0.42 | 1.15±0.36 | 5.22±0.55 | 1.30×10−19 | |
| hsa-miR-3653-5p | 0.59±0.42 | 1.30±0.28 | 5.21±0.50 | 6.41×10−24 | |
| hsa-miR-1251-5p | 0.78±0.53 | 1.38±0.24 | 4.06±0.58 | 3.62×10−15 | |
| hsa-miR-2681-5p | 0.43±0.40 | 1.04±0.40 | 4.06±0.57 | 1.09×10−19 | |
| hsa-miR-509-3-5p | 1.25±0.46 | 1.85±0.17 | 4.05±0.49 | 3.45×10−18 | |
| hsa-miR-1246 | 1.66±0.66 | 2.26±0.17 | 4.00±0.68 | 1.08×10−12 | |
| hsa-miR-1271-3p | 2.00±0.92 | 2.60±0.19 | 4.00±0.94 | 2.90×10−8 | |
a, P values were calculated by the paired t-test. SD, standard deviation; PR, partial response; SD, stable disease; PD, progressive disease; FPKM, fragments per kilobase of exon per million fragments mapped.