Table 1.
Characteristics of participants in the UK Biobank included in the analyses.
| Died |
|||||
|---|---|---|---|---|---|
| Alive at the End of Follow-Up | Died During Follow-Up | Total | Dementia related death | Other Cause of Death | |
| N (%) | 233,253 (96%) | 9,705 (4%) | 242,958 | 552 (6%) | 9,153 (94%) |
| Baseline Age, mean (SD) | 62.5 (3.8) | 63.9 (3.8) | 62.51 (3.8) | 64.4 (3.6) | 63.84 (3.8) |
| Years of follow up, median (SD) | 7.67 (0.86) | 4.89 (2.03) | 7.58 (1.1) | 5.65 (1.86) | 4.84 (2.03) |
| Female N (%) | 125,413 (54%) | 3,653 (38%) | 129,066 (53%) | 209 (38%) | 3,444 (38%) |
| APOE-e4, N (%) | 60,724 (26%) | 2641 (27%) | 63,365 (26%) | 204 (37%) | 2,437 (27%) |
| AD GRS, mean (SD) | 0.04 (0.40) | 0.05 (0.41) | 0.04 (.40) | 0.16 (0.47) | 0.04 (0.41) |
| AD GRS without APOE-e4, mean (SD) | −0.14 (0.17) | −0.14 (0.18) | −0.14 (0.17) | −0.12 (0.18) | −0.14 (0.17) |
| Verbal Numeric Reasoning, mean (SD) | 6.09 (2.07) | 5.73 (2.05) | 6.07 (2.07) | 5.08 (2.06) | 5.75 (2.05) |
| High education, N (%) | 101,869(44%) | 3,460 (36%) | 105,329 (43%) | 213 (39%) | 3,347 (35%) |
| Any Hospitalization | 159,511 (68%) | 8,145 (84%) | 167,656 (69%) | 466 (84%) | 7679 (84%) |
| Hospitalization due to falls | 11,147 (5%) | 1,004 (10%) | 12,151 (5%) | 105 (19%) | 1004 (10%) |
| Hospitalization due to UTIs | 7,658 (3%) | 1,462 (15%) | 9,120 (4%) | 150 (27%) | 1462 (15%) |