. Author manuscript; available in PMC: 2020 Jul 1.

Published in final edited form as: Alzheimers Dement. 2019 Jul;15(7):907–916. doi: 10.1016/j.jalz.2019.04.005

Table 4.

Association of AD Genetic Risk Score (AD GRS) with Hospitalizations (rate), Hospitalization due to falls, Hospitalization due to UTIs.

	Hospitalization	Hospitalization-Falls	Hospitalization-UTIs	Hospitalization-Falls or UTIs
	IRR(95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
Model 1
AD-GRS	1.01 (1.01–1.02)	1.06 (1.01,1.10)	1.04 (0.99, 1.10)	1.04 (1.01, 1.08)
Model 2
AD-GRS	1.01 (1.01–1.02)	1.06 (1.01,1.10)	1.04 (0.99, 1.10)	1.04 (1.01, 1.08)
Low Education	1.25 (1.24, 1.26)	1.15 (1.10, 1.19)	1.33 (1.27, 1.39)	1.20 (1.16,1.24)
Model 3
AD-GRS	1.01 (0.999–1.02)	1.01 (.94, 1.09)	0.99 (0.91, 1.08)	1.01 (0.95,1.07)
Low Education	1.25 (1.24, 1.26)	1.14 (1.10, 1.19)	1.33 (1.27, 1.39)	1.20 (1.16,1.23)
AD-GRS by Low Education Interaction	1.01 (0.992–1.02)	1.07 (0.98, 1.8)	1.08 (0.97, 1.20)	1.07 (0.99,1.14)
AD-GRS Effect Estimates Among High and Low Education Groups, Estimated from Model 3
AD-GRS in High Education	1.008 (0.999–1.02)	1.01 (.94, 1.09)	0.99 (0.91, 1.08)	1.01 (0.95,1.07)
AD-GRS in Low Education	1.013 (1.01,1.02)	1.08 (1.02,1.15)	1.07 (1.00, 1.14)	1.07 (1.02, 1.12)
P_interaction	0.42	0.14	0.18	0.10