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P6 NPs mediation of an antitumor effect in a A2780 xenograft model. (a) Tumor growth curve of each mouse from different groups of A2780 tumor-bearing athymic nude mice during chemotherapy (n = 5). (b) The harvested A2780 xenograft tumors after systemic treatment captured using the Maestro 2 in vivo imaging system. (c) Western blot quantification of p53, Caspase 3, PARP, and cleaved PARP for A2780 xenograft tumors following treatment with PBS, cisplatin, P6 NPs, P6 Soln, or DP 3000.
