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. 2019 Oct 16;21(2):e127–e138. doi: 10.1093/pm/pnz249

Table 2.

Opioid- and non-opioid-taking group comparisons across all PROMIS and Pain Intensity measures

Currently Taking Opioid Medications
Not Currently Taking Opioid Medications
No. (Missing Data) M SD No. (Missing Data) M SD P Cohen’s d
PROMIS Global Health
 Mental Score 671 (6.68%) 41.49 9.24 452 (4.64%) 43.65 8.99 <0.001* 0.24
 Physical Score 671 (6.68%) 36.14 6.89 452 (4.64%) 39.67 8.10 <0.001* 0.47
PROMIS
 Pain Interference 697 (3.06%) 65.09 6.63 473 (0.21%) 62.12 8.15 <0.001* 0.40
 Pain Behavior 692 (3.76%) 59.25 3.59 472 (1.05%) 57.54 5.14 <0.001* 0.39
 Physical Function 690 (4.03%) 34.69 7.64 469 (1.69%) 38.36 9.22 <0.001* 0.44
 Fatigue 687 (4.45%) 60.18 8.99 466 (1.69%) 58.05 10.19 <0.001* 0.22
 Depression 687 (4.45%) 54.63 9.80 464 (2.11%) 52.85 9.74 <0.005* 0.18
 Anxiety 684 (4.87%) 54.81 9.59 462 (2.53%) 54.65 9.81 0.78 0.02
 Anger 677 (5.84%) 49.23 10.21 458 (3.38%) 49.22 9.91 0.98 0.00
 Sleep Disturbance 683 (5.10%) 57.50 8.85 462 (2.53%) 55.79 8.94 0.001* 0.19
 Sleep Impairment 681 (5.29%) 56.92 8.93 462 (2.53%) 55.89 10.27 0.08 0.11
 Emotional Support 670 (6.82%) 51.69 9.49 450 (5.06%) 51.48 9.05 0.71 0.02
 Satisfaction with Social Roles and Activities 666 (7.37%) 40.36 8.86 450 (5.06%) 43.87 9.07 <0.001* 0.39
 Social Isolation 663 (7.79%) 48.04 9.80 448 (5.49%) 47.29 9.78 0.21 0.08
Pain Intensity
 Worst 719 (0%) 8.05 1.71 474 (0%) 6.80 2.46 <0.001* 0.60
 Average 719 (0%) 5.90 1.92 474 (0%) 5.01 2.38 <0.001* 0.41
 Now 719 (0%) 5.69 2.27 474 (0%) 4.55 2.62 <0.001* 0.47
 Least 719 (0%) 3.83 2.31 474 (0%) 3.09 2.47 <0.001* 0.31
Pain Intensity Composite 719 (0%) 5.87 1.73 474 (0%) 4.86 2.20 <0.001* 0.51
Negative Affect Composite 677 (5.84%) 52.87 8.96 458 (3.38%) 52.25 8.97 0.26 0.07

The composite Pain Intensity is an average of the four Pain Intensity measures. The composite negative affect is an average of PROMIS Anxiety, Anger, and Depression.

PROMIS = Patient-Reported Outcomes Measurement Information System.

*

Bonferroni corrected.