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. 2019 Oct 16;21(2):e127–e138. doi: 10.1093/pm/pnz249

Table 4.

Results of a stepwise regression analysis with Rx-Misuse as the dependent variable

Beta P Tolerance F(df) P Adjusted R2 F(df) Change P of F Change
Model 1 F(4,645) = 6.01 <0.001 0.04 F(4,645) = 6.01 <0.001
 Sex 0.18 <0.001 0.99
 Age –0.01 0.78 0.98
 Ethnicity –0.03 0.49 0.86
 Race –0.06 0.19 0.85
Model 2 F(5,644) = 25.85 <0.001 0.16 F(1,644) = 101.45 <0.001
 Sex 0.19 <0.001 0.99
 Age 0.02 0.53 0.98
 Ethnicity –0.03 0.40 0.86
 Race –0.03 0.41 0.85
 PROMIS Anxiety 0.37 <0.001 0.99
Model 3 F(6,643) = 23.86 <0.001 0.17 F(1,643) = 11.75 <0.001
 Sex 0.18 <0.001 0.99
 Age 0.04 0.29 0.96
 Ethnicity –0.03 0.45 0.86
 Race –0.04 0.37 0.85
 PROMIS Anxiety 0.24 <0.001 0.48
 PROMIS Anger 0.18 <0.001 0.48
Model 4 F(7,642) = 21.54 <0.001 0.18 F(1,642) = 6.41 0.01
 Sex 0.18 <0.001 0.99
 Age 0.04 0.29 0.96
 Ethnicity –0.03 0.45 0.86
 Race –0.03 0.37 0.85
 PROMIS Anxiety 0.23 <0.001 0.48
 PROMIS Anger 0.17 <0.001 0.47
 Pain Intensity–Worst 0.09 0.01 0.96
Final Model F(8,641) = 19.47 <0.001 0.19 F(1,641) = 4.23 0.04
 Sex 0.18 <0.001 0.99
 Age 0.04 0.29 0.95
 Ethnicity –0.03 0.45 0.86
 Race –0.03 0.37 0.85
 PROMIS Anxiety 0.15 0.01 0.32
 PROMIS Anger 0.13 0.02 0.42
 Pain Intensity–Worst 0.09 0.02 0.95
 PROMIS Depression 0.13 0.04 0.33

The first step included all demographic measures as independent variables, and all PROMIS and Pain Intensity measures were subsequently added in a stepwise process. The final model included all significant predictors above and beyond the demographic measures. No other measures resulted in a significant contribution.

PROMIS = Patient-Reported Outcomes Measurement Information System.