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. 2020 Feb 4;105(3):e858–e870. doi: 10.1210/clinem/dgaa055

Table 4.

Mean heart rate (beats per minute, SE) adjusted for time of day of examination by hemoglobin A1c level among adults with diagnosed diabetes age 20 years or older, NHANES 2011 to 2016

Diagnosed Diabetes
A1c <53 mmol/mol (<7.0%) (N = 1029) (Reference) A1c 53-<75 mmol/mol (7.0% -<9.0%) (N = 730) A1c 65-<97 mmol/mol (9.0% - <11.0%) (N = 217) A1c ≥97 mmol/mol (≥11.0%) (N = 147)
Overall 73 (0.7) 74 (0.6) 78 (1.1)b 80 (1.4)b
Age, y
 20 to 44 78 (1.3) 80 (1.8) 85 (2.6)a 82 (2.1)
 45 to 64 73 (0.9) 76 (0.7)a 77 (1.5)a 80 (2.1)a
 ≥ 65 71 (0.9) 70 (0.9) 73 (2.4) 78 (1.6)b
Sex
 Men 73 (0.8) 73 (0.6) 77 (1.8)a 77 (1.9)a
 Women 73 (0.8) 76 (1.2)a 79 (1.4)a 84 (1.7)b
Race/Ethnicity
 All Hispanic 72 (0.7) 75 (0.8)a 82 (1.8)b 80 (1.9)b
 Mexican American 72 (1.1) 75 (1.2)a 82 (2.0)b 79 (2.3)a
 Non-Hispanic white 74 (0.9) 74 (0.9) 78 (1.7)a 78 (3.7)
 Non-Hispanic black 72 (0.8) 75 (1.0)a 77 (2.9) 82 (1.5)b
Education
 < High school 72 (0.7) 75 (1.0)a 78 (1.6)a 83 (1.8)b
 High school/GED 73 (1.2) 71 (1.3) 79 (1.5)a 75 (2.7)
 ≥ High school 73 (1.0) 76 (0.9) 77 (1.7)a 82 (1.8)b
PIR
 ≤ 1.00 75 (0.9) 76 (1.2) 79 (1.7)a 81 (2.8)
 > 1.00 72 (0.7) 74 (0.7)a 78 (1.2)b 81 (1.6)b
Health insurance coverage
 Yes 73 (0.7) 75 (0.6) 77 (1.1)b 79 (1.6)b
 No 75 (1.3) 73 (1.2) 82 (2.3)a 84 (1.8)a
Smoking status
 Current 79 (2.4) 77 (1.8) 79 (2.8) 79 (1.8)
 Former 72 (1.1) 73 (1.5) 77 (2.1)a 76 (3.0)
 Never 72 (0.8) 74 (0.8) 78 (1.7)a 83 (1.9)b
Sleep, h
 < 7 71 (0.9) 75 (0.9)a 78 (1.5)b 79 (1.2)b
 ≥ 7 73 (0.8) 74 (1.0) 78 (1.2)b 81 (1.8)b
Work time activity
 Yes 74 (0.7) 73 (0.9) 80 (2.3)a 77 (1.9)
 No 72 (0.9) 75 (0.8)a 76 (1.34)a 82 (1.7)b
Leisure time activity
 Yes 72 (0.8) 75 (1.1) 78 (2.3)a 80 (2.3)b
 No 73 (0.8) 74 (0.6) 78 (1.2)a 81 (1.6)b
BMI, kg/m2
 < 25.0 73 (2.3) 73 (1.1) 76 (4.4) 80 (3.2)
 25.0–29.9 73 (0.9) 73 (1.2) 80 (1.7)b 75 (2.9)
 ≥ 30.0 73 (0.8) 75 (0.8) 78 (1.5)a 83 (1.1)b
Waist circumference
 High risk (> 88 cm for women; >102 cm for men) 73 (0.7) 75 (0.8) 78 (1.2)a 82 (1.6)b
 Low risk (≤ 88 cm for women; ≤ 102 cm for men) 72 (1.8) 72 (1.1) 80 (3.4) 77 (2.9)
Hypertension, self-report
 Yes 73 (0.9) 75 (0.8) 77 (1.4)a 80 (1.9)a
 No 72 (0.8) 74 (1.1) 79 (1.6)b 81 (1.7)b
History of CVD
 Yes 67 (1.1) 69 (1.0) 72 (3.1) 75 (4.5)
 No 74 (0.7) 76 (0.6) 79 (1.0)b 81 (1.2)b
eGFR, mL/min per 1.73 m2
 < 60 70 (1.3) 72 (1.5) 74 (2.0) 83 (2.8)b
 ≥ 60 74 (0.8) 75 (0.7) 78 (1.23)b 80 (1.7)a
ACE inhibitor or ARB
 Yes 73 (0.9) 74 (0.8) 76 (1.4) 81 (2.3)a
 No 72 (0.8) 74 (1.0) 80 (1.5)b 80 (1.4)b
β-blockers
 Yes 68 (0.7) 68 (1.2) 73 (2.4)a 79 (4.5)a
 No 75 (0.8) 77 (0.7)a 79 (1.1)b 81 (1.1)b
Diuretics
 Yes 73 (1.2) 74 (1.2) 76 (1.7) 79 (2.5)a
 No 73 (0.7) 74 (0.6)a 78 (1.3)b 81 (1.7)b
CA-channel blockers
 Yes 73 (1.7) 73 (1.0) 78 (2.7) 80 (4.8)
 No 73 (0.7) 75 (0.8) 78 (1.1)b 80 (1.1)b
Taking statin
 Yes 72 (1.0) 73 (0.7) 73 (1.8) 78 (2.6)a
 No 74 (0.8) 76 (1.0)a 82 (1.2)b 82 (1.6)b

Abbreviations: ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; BMI, body mass index; CA, calcium; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; GED, General Educational Development; HbA1c, hemoglobin A1c; NHANES, National Health and Nutrition Examination Survey, PIR, poverty income ratio.

a P less than .05 vs HbA1c less than 7.0%.

b P less than .001 vs HbA1c less than 7.0%.